Papers

Papers Citing Our Services

Discovery of a proteinaceous cellular receptor for a norovirus. Orchard et al., Science 2016

Blood Group O–Dependent Cellular Responses to Cholera Toxin: Parallel Clinical and Epidemiological Links to Severe Cholera. Kuhlmann et al., Am J Trop Med Hyg 2016

Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival. Redmann et al., Sci Rep 2016

Multiple Domains of GlcNAc-1-Phosphotransferase Mediate Recognition of Lysosomal Enzymes. Van Meel et al., JBC 2016

A Puromycin Selectable Cell Line for the Enrichment of Mouse Embryonic Stem Cell-Derived V3 Interneurons. Xu et al., Stem Cell Research & Therapy 2015

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells. Selleck et al., MBio 2015

A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome. Lu et al., PNAS 2014

Genome Engineering and Stem Cell Technology Papers by Our Scientists

Donor plasmid design for codon and single base genome editing using zinc finger nucleases. Pruett-Miller, et al., Methods Mol Biol 2015

Gene editing using ssODNs with engineered endonucleases. Chen et al., Methods Mol Biol 2015

Preface. Chromosomal mutagenesis. Pruett-Miller, Methods Mol Biol 2015

High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs. Duda  et al., Nucleic Acids Res 2014

Nuclease-mediated gene editing by homologous recombination of the human globin locus. Voit et al., Nucleic Acids Res 2014

Genome editing in mouse spermatogonial stem/progenitor cells using engineered nucleases. Fanslow et al., PLoS One 2014

Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects. Connelly et al., Blood 2014

A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome. Lu et al., PNAS 2014

A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype. Ellis et al., Virol J 2013

Expanding the Repertoire of Target Sites for Zinc Finger Nuclease-mediated Genome Modification. Wilson et al., Mol Ther Nucleic Acids 2013

High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases. Chen et al., Nat Methods 2011

Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease. Connelly et al., Mol Ther 2010

Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels. Pruett-Miller et al., PLoS Genet 2009

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al., Cell Stem Cell 2009

Comparison of zinc finger nucleases for use in gene targeting in mammalian cells. Pruett-Miller et al., Mol Ther 2008

Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification. Maeder et al., Mol Cell 2008

A look to future directions in gene therapy research for monogenic diseases. Porteus et al., PLoS Genet 2006